Seminars & Events

Computing, Environment and Life Sciences
"Salmonella: Comparative Genomics and High-throughput Genetics"

DATE: December 17, 2012
TIME: 10:00 AM - 11:00 AM
SPEAKER: Dr. Michael McClelland, Professor, Vaccine Research Institute of San Diego, and Department of Pathology, University of Calif
LOCATION: Building 240, Conference Room 1404, Argonne National Laboratory

Description:
We are investigating the genome diversity and genetics of the common foodborne human pathogen Salmonella. Closer inspection of the evolution and phylogenetic structure of this diverse species will help us to understand how the genetic differences between isolates of this species impact on survival strategies of the bacterium. In addition to these evolutionary studies, we are also developing genetic methods to efficiently screen fitness phenotypes of mutants. In our approaches we focus not only on mechanisms of animal infection but also seek to characterize the interaction of Salmonella with the host microbiome and the bacterium’s survival mechanisms outside animal hosts.

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