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Institute for Genomics & Systems Biology and Center for Nanoscale Materials
"Nucleic Acid Sequence Is a Universal Information Substrate of All Life"

DATE: February 16, 2007
TIME: 10:00am
SPEAKER: Viktor Stolc, Director, NASA Ames Genome Research Facility
LOCATION: Bldg. 440, A105 & A106, Argonne National Laboratory
HOST: Kevin White, IGSB and Eric Isaacs, CNM

Description:
In partnership with several universities, NASA Ames Genome Research Facility has developed novel applications of high-density DNA oligonucleotide microarrays for probing RNA expression of both protein-coding and non-protein-coding sequences in the completed genomes of several model organisms and the human genome. Computational methods for the design and analysis of the whole-genome tiling microarrays were developed by using the NASA Ames supercomputer. This work resulted in the confirmation of nearly all previous gene expression results generated with other techniques, and identified thousands of genes and RNA transcripts that were previously undescribed by all other methods.


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