Seminars & Events

IGSB Seminar Series
"Evidence and Inference: Comparative Biology in the Age of Genomics"

DATE: February 5, 2009
TIME: 4:00 PM - 5:00 PM
SPEAKER: Judith Blake, Associate Professor, Jackson Laboratory
LOCATION: GCIS W301, University of Chicago

Description:
The activities of my research group and collaborations focus on the development of bioinformatics systems essential for functional genomics, genetics and phenotypic research. The sequencing of mouse, human and other genomes and the rapid accumulation of very large data sets has resulted in an overwhelming amount of information from multiple sources containing a variety of content and formats. The challenge is to bring all the data together and make it easily accessible to researchers directly and/or for additional computer analysis. Our current research centers on combining bio-ontologies (defined, controlled, structured vocabularies) and database systems to identify molecular elements that contribute to the processes of particular diseases, such as lung cancer. This work is undertaken as part of the Gene Ontology Consortium, a group of 19 model organism databases and genome annotation centers. My group, as part of the Mouse Geneome Informatics Consortiun at The Jackson Laboratory, is responsible for the functional and comparative annotation of mouse genes.

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