Seminars & Events

Mathematics and Computer Science Division Seminar
"Learning how to read genomes"

DATE: April 15, 2010
TIME: 10:30 AM - 11:30 AM
SPEAKER: Alice McHardy, Max-Planck-Institut für Informatik
LOCATION: Bldg. 240, Conference Room 4301, Argonne National Laboratory

Description:
Technological advances have enabled whole genome sequencing of organisms from a wide range of taxa and surveys of genome-wide genetic diversity for microbial, viral and eukaryotic populations. A major challenge is the development of computational methods for analysis of these novel large-scale data sets. Such methods promise to deliver a more detailed understanding of biological processes with relevance for medical, biotechnological, agricultural and environmental applications. I will present an overview of the group’s research, which focuses on the computational analysis of metagenomic and population-level genomic data sets. In the area of metagenomics we are working on methods for the sequence-composition based ‘binning’ or taxonomic assignment of metagenome sequence fragments. We are furthermore seeking to understand and detect the imprint of selection from population-level genomics data, with a particular focus on understanding (and predicting) the evolution of influenza A virus.

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