Argonne National Laboratory

Interactions of Semiflexible Filaments and Molecular Motors

TitleInteractions of Semiflexible Filaments and Molecular Motors
Publication TypeJournal Article
Year of Publication2007
AuthorsKarpeev, DA, Aranson, IS, Tsimring, LS, Kaper, HG
JournalPhys. Rev. E
Issue(Pt. 1)
Other NumbersANL/MCS-P1381-1206

This paper summarizes the results of numerical simulations of the interaction of a pair of biofilaments mediated by a molecular motor. The filaments are modeled as flexible rods, and the results are applicable to microtubules, which are relatively stiff, as well as to much softer formation and the rheology of semiflexible filament networks. The simulations are based on a nonlinear elasticity equation. The results show that flexibility enhances the tendency of the filaments to align. The enhancement in turn favors the formation of large-scale structures in multifilament systems. Simulations for soft filaments show that the action of the motor can result in the formation of multiple loops of the filaments as a result of buckling.